Dichloromethane → HCID 43654526, compound

HRID 861904Notes

Reaction equation

HRID 861904 reaction equation
[Cl:1][CH2:2][CH2:3][CH2:4][S:5](Cl)(=[O:7])=[O:6].[CH:9]([NH2:12])(C)[CH3:10].[CH2:13](Cl)Cl>>[Cl:1][CH2:2][CH2:3][CH2:4][S:5]([N:12]([CH3:13])[CH2:9][CH3:10])(=[O:7])=[O:6]

Participants

4

Reactant 3

HCID 6344DichloromethaneHCID 6363IsopropylamineHCID 154103-Chloropropanesulphonyl chloride

Product 1

HCID 43654526HCID 43654526, compoundYield 89%

Procedure

3-Chloropropanesulfonyl chloride (2.54 g) is dissolved in methylene chloride and isopropylamine (1.90 g) is added dropwise under ice cooling. After stirring at room temperature for 2 hours, the solution is extracted with methylene chloride and water to give crude 3-chloropropanesulfonyl methylethylamine (2.54 g, 89%) as pale yellow liquid.

Workup

  1. extractionthe solution is extracted with methylene chloride and water

Sources & evidence

ORD record
ord-af540c742285482391a8317c7bdd7a84
Source dataset
uspto-grants-1998_02
Patent number
US05716950

Reaction notes

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