HuagongsheHuagongshe Chemistry Print Report · For research reference only
Diazomethane → 2-(3-Nitrobenzoyl)-3-methoxycarbonylpyridine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Diazomethane | HCID 9550 | — |
| Reactant | 2-(3-Nitrobenzoyl)-3-carboxypyridine | HCID 19700795 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | 2-(3-Nitrobenzoyl)-3-methoxycarbonylpyridine | HCID 19700716 | — |
Reaction Steps
2-(3-Nitrobenzoyl)-3-carboxypyridine was dissolved in 20 ml of methylene chloride and the solution was cooled in an ice/water bath. Diazomethane (25 ml, 0.33M) was added to the solution and stirred for 2 hours. The solvent was removed and the residue chromatographed (methylene chloride) yielding 0.26 g of 2-(3-nitrobenzoyl)-3-methoxycarbonylpyridine.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05716954 |
| Source dataset | uspto-grants-1998_02 |
| ORD ID | ord-667a28e15a2c46cdb454835928c70ac3 |
| Source note | uspto-grants-1998_02 |