HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 862001Generated: October 29, 2026
Potassium Cyanide → Ethyl 5-(cyanomethyl)imidazo[1,2-a]pyridine-2-carboxylate
https://huagongshe.com/reaction/862001
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Potassium Cyanide | HCID 9032 | — |
| Reactant | Ethyl 5-(chloromethyl)imidazo[1,2-a]pyridine-2-carboxylate | HCID 19701283 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | Ethyl 5-(cyanomethyl)imidazo[1,2-a]pyridine-2-carboxylate | HCID 19701198 | — |
Reaction Steps
Title material is made by dissolving the title product of Example 5 in DMF and after cooling to 0° C., reacting with KI and KCN. The reaction is stirred for 6 h at 0° C. After warming to room temperature, title compound is obtained by diluting with CHCl3, washing with water, and removing all solvent in vacuo.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US05716964 |
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| Source dataset | uspto-grants-1998_02 |
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| ORD ID | ord-a9f32087fa6042738af023682b205495 |
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| Source note | uspto-grants-1998_02 |
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