HuagongsheHuagongshe Chemistry Print Report · For research reference only
Tributyltin azide → Ethyl 5-(1H-tetrazol-5-ylmethyl)imidazo[1,2-a]pyridine-2-carboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Tributyltin azide | HCID 4984872 | — |
| Reactant | Ethyl 5-(cyanomethyl)imidazo[1,2-a]pyridine-2-carboxylate | HCID 19701198 | — |
| Solvent | HCID 19701381 | HCID 19701381 | — |
| Product | Ethyl 5-(1H-tetrazol-5-ylmethyl)imidazo[1,2-a]pyridine-2-carboxylate | HCID 178469441 | — |
Reaction Steps
The title material is prepared by heating the title product of Example 99 with azido tributylstannane at 80° C. for 72 h. After cooling to room temperature, the reaction is treated with methanolic HCl for 30 min., diluted with 4N HCl, washed with diethyl ether and concentrated to yield title material.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05716964 |
| Source dataset | uspto-grants-1998_02 |
| ORD ID | ord-1add0950defb45b38b2876b3671ad414 |
| Source note | uspto-grants-1998_02 |