Acetyl chloride → HCID 19701924, compound

Participants

Reaction Steps

2-Amino-5-chloro-N-(3,4-methylenedioxybenzyl)benzamide hydrochloride (100 mg) was reacted with 40 μl of acetyl chloride in 5 ml of tetrahydrofuran in the presence of 150 μl of diisopropylethylamine. The reaction mixture was subjected to extraction with ethyl acetate and water and recrystallization from ethyl acetate/hexane to give 85 mg of 2-acetamido-5-chloro-N-(3,4-methylenedioxybenzyl)benzamide (yield: 84%).

Provenance & Evidence