Acetic Acid → 15023-39-9

Participants

Reaction Steps

Compound 4 (27.0 g; 0.062 mole) and Zn° (16.2 g; 0.249 mol) were combined in HOAc (100 ml) and heated to reflux for one half hour. The reaction mixture was cooled and filtered through Celite®. The filtrate was concentrated and the residue suspended in H2O, whereupon the oil crystallized. The solid was filtered, washed with H2O and suction dried to yield 18.4 g (96.8%) of Compound 5 as a white solid.

Provenance & Evidence