HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethylenediamine → Pixantrone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethylenediamine | HCID 3301 | — |
| Reactant | 6,9-Difluorobenzo[g]isoquinoline-5,10-dione | HCID 10105904 | — |
| Product | Pixantrone | HCID 134019 | — |
Reaction Steps
The reported synthetic procedures use, as a key intermediate, 6,9-difluorobenzo[g]isoquinoline-5,10-dione. This compound is reacted with ethylene-diamine which produces the desired 6,9-bis[(2-aminoethyl)amino]benzo[g]isoquinoline-5,10-dione.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05717099 |
| Source dataset | uspto-grants-1998_02 |
| ORD ID | ord-ad59f8e401364869b1edae45065afc8e |
| Source note | uspto-grants-1998_02 |