HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-(2-Methoxyphenyl)propan-2-amine → N-[1-(2-Methoxyphenyl)-1-methylethyl]-3-cyanoandrosta-3,5-diene-17beta-carboxamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-(2-Methoxyphenyl)propan-2-amine | HCID 15310856 | — |
| Reactant | S-2pyridyl 3-cyanoandrosta-3,5-diene-17beta-thiocarboxylate | HCID 15380265 | — |
| Product | N-[1-(2-Methoxyphenyl)-1-methylethyl]-3-cyanoandrosta-3,5-diene-17beta-carboxamide | HCID 67646664 | 96% |
Reaction Steps
Following a procedure similar to that described in Example 3(b), but using S-2-pyridyl 3-cyanoandrosta-3,5-diene-17β-thiocarboxylate [prepared as described in Example 3(a)] and 1-(2-methoxyphenyl)-1-methylethylamine (prepared as described in Preparation 10c) as starting materials, in relative proportions similar to those used in that Example, the title compound was obtained in a yield of 96%.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05717088 |
| Source dataset | uspto-grants-1998_02 |
| ORD ID | ord-a28d9bad24dd40a68a576dd72b801faf |
| Source note | uspto-grants-1998_02 |