HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-[Amino(phenyl)methyl]phenol → N-(4-Hydroxybenzhydryl)-3-cyanoandrosta-3,5-diene-17beta-carboxamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-[Amino(phenyl)methyl]phenol | HCID 4962203 | — |
| Reactant | S-2pyridyl 3-cyanoandrosta-3,5-diene-17beta-thiocarboxylate | HCID 15380265 | — |
| Product | N-(4-Hydroxybenzhydryl)-3-cyanoandrosta-3,5-diene-17beta-carboxamide | HCID 15380270 | 83% |
Reaction Steps
Following a procedure similar to that described in Example 3(b), but using S-2-pyridyl 3-cyanoandrosta-3,5-diene-17β-thiocarboxylate [prepared as described in Example 3(a)] and 4-hydroxybenzhydrylamine (prepared as described in Preparation 13) as starting materials, in relative proportions similar to those used in that Example, the title compound was obtained in a yield of 83%.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05717088 |
| Source dataset | uspto-grants-1998_02 |
| ORD ID | ord-24d0d19fa7c448c4961a7d5e3c4ad984 |
| Source note | uspto-grants-1998_02 |