Methyl 4-methylbenzoate → 2-(4-Methylphenyl)propan-2-amine

HRID 862309Notes

Reaction equation

HRID 862309 reaction equation
CO[C:3]1[CH:8]=[CH:7][C:6]([C:9]([NH2:12])([CH3:11])[CH3:10])=[CH:5][CH:4]=1.[CH3:13]C1C=CC(C(OC)=O)=CC=1>>[CH3:13][C:3]1[CH:8]=[CH:7][C:6]([C:9]([NH2:12])([CH3:11])[CH3:10])=[CH:5][CH:4]=1

Participants

3

Reactant 2

HCID 7455Methyl 4-methylbenzoateHCID 110082782-(4-Methoxyphenyl)propan-2-amine

Product 1

HCID 5840502-(4-Methylphenyl)propan-2-amineYield 34%

Procedure

Following a procedure similar to that described in Preparation 10a, but using methyl 4-methylbenzoate as a starting material, in a relative amount similar to that used in that Preparation, the title compound was obtained in a yield of 34%.

Workup

  1. customin a relative amount similar to that used in that Preparation

Sources & evidence

ORD record
ord-bb8b7bac9ecc4ef3b107e01ad97c2d0d
Source dataset
uspto-grants-1998_02
Patent number
US05717088

Reaction notes

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