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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 862317Generated: October 25, 2026

2-(4-Methoxyphenyl)propan-2-amine → N-[1-(4-methoxyphenyl)-1-methylethyl]-3-cyanoandrosta-3,5-diene-17beta-carboxamide

https://huagongshe.com/reaction/862317

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(4-Methoxyphenyl)propan-2-amineHCID 11008278—
Reactant3-Cyanoandrosta-3,5-diene-17beta-carboxylic acidHCID 15380254—
ProductN-[1-(4-methoxyphenyl)-1-methylethyl]-3-cyanoandrosta-3,5-diene-17beta-carboxamideHCID 1538026393%

Reaction Steps

Following a procedure similar to that described in Preparation 16a, but using 3-cyanoandrosta-3,5-diene-17β-carboxylic acid [prepared as described in Example 1(b)] and 1-(4-methoxyphenyl)-1-methylethylamine as starting materials, in relative proportions similar to those used in that Preparation, the title compound was obtained in a yield of 93%.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05717088
Source datasetuspto-grants-1998_02
ORD IDord-91b4f0e04e284b6b82d20308050e7737
Source noteuspto-grants-1998_02