Water → HCID 15157151, compound

HRID 862419Notes

Reaction equation

HRID 862419 reaction equation
[O-:1][C:2]#[N:3].[Na+].O.[NH2:6][C:7]1[CH:8]=[C:9]([CH:13]=[CH:14][CH:15]=1)[C:10]([NH2:12])=[O:11]>C(O)(=O)C>[NH:6]([C:7]1[CH:8]=[C:9]([CH:13]=[CH:14][CH:15]=1)[C:10]([NH2:12])=[O:11])[C:2]([NH2:3])=[O:1]

Participants

5

Reactant 3

HCID 962WaterHCID 16453-AminobenzamideHCID 517096Sodium Cyanate

Product 1

HCID 15157151HCID 15157151, compoundYield 78.1%

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent

Procedure

Sodium cyanate (1.3 gm, 20 mMole) in 9.0 ml or water was added over a 15 minute period to a solution of 3-aminobenzamide (1.36 gm, 10 mMole) in acetic acid at 35° C. The mixture was stirred for a further 15 minutes during which time a white precipitate formed. This was filtered off, washed with cold water and crystallized from 25% ethanol to give 1.4 gm (78%) of shiny crystals. m.p. >300° C.

Workup

  1. customformed
  2. filtrationThis was filtered off
  3. washwashed with cold water
  4. customcrystallized from 25% ethanol

Sources & evidence

ORD record
ord-b97dc23f4c47492bbcd82523036583c8
Source dataset
uspto-grants-1998_02
Patent number
US05719151

Reaction notes

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