反应详情

The compound (0.15 g) obtained in Example 1 was suspended in ethanol (10 ml), a 1N aqueous sodium hydroxide solution (1.5 ml) was added, and the mixture was stirred overnight. The solvent was distilled off under reduced pressure, a 3N aqueous hydrochloric acid solution was added, and the formed precipitate was filtered, washed with water, and dried under reduced pressure to obtain the entitled compound (0.09 g).

1. distillationThe solvent was distilled off under reduced pressure
2. additiona 3N aqueous hydrochloric acid solution was added
3. filtrationthe formed precipitate was filtered
4. washwashed with water
5. customdried under reduced pressure