Methyl iodide → 2-[(1-Methyl-1H-imidazol-5-yl)methoxy]-1-(naphthalen-1-yl)ethan-1-ol

HRID 862526Notes

Reaction equation

[NH:1]1[C:5]([CH2:6][O:7][CH2:8][CH:9]([C:11]2[C:20]3[C:15](=[CH:16][CH:17]=[CH:18][CH:19]=3)[CH:14]=[CH:13][CH:12]=2)[OH:10])=[CH:4][N:3]=[CH:2]1.[CH3:21]I>>[CH3:21][N:1]1[C:5]([CH2:6][O:7][CH2:8][CH:9]([C:11]2[C:20]3[C:15](=[CH:16][CH:17]=[CH:18][CH:19]=3)[CH:14]=[CH:13][CH:12]=2)[OH:10])=[CH:4][N:3]=[CH:2]1

Participants

Reactant 2

HCID 6328Methyl iodide

HCID 30766422-[(1H-Imidazol-5-yl)methoxy]-1-(naphthalen-1-yl)ethan-1-ol

Product 1

HCID 30766692-[(1-Methyl-1H-imidazol-5-yl)methoxy]-1-(naphthalen-1-yl)ethan-1-ol

Procedure

2-(Imidazol-5-yl)methoxy-l-(1-naphthyl)-ethanol was reacted with methyl iodide to obtain oily 2-(1-methylimidazol-5-yl)methoxy-1-(1-naphthyl)ethanol (compound No. 283).

Sources & evidence

ORD record: ord-fcde9ce1927c4b019ca5ac9b9b0bd6da
Source dataset: uspto-grants-1998_02
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05719150

Reaction notes

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