(5-Methyl-2-nitrophenyl)methanol → 5-Methyl-2-nitrobenzaldehyde

Participants

Reaction Steps

A mixture of 3-methyl-6-nitrobenzylalcohol (10 g, 59.8 mmol) and manganese dioxide (80 g) in dichloromethane (100 mL) was stirred for 9 h and passed through a celite short column. The eluent was concentrated and the residue was purified by silica gel column chromatography with 8:1 hexane/ethyl acetate to give 8.25 g of the title compound (84%).

Provenance & Evidence