反应详情

A mixture of benzyl 4-(1-imidazolyl)butyrate (7.4 g), palladium-carbon (5%)(1.0 g) and ethanol (400 ml) was subjected to catalytic hydrogenation at room temperature and 1 atm. The catalyst was filtered off, the filtrate was concentrated under reduced pressure, and the crystals were recrystallized from ethanol to give 4-(1-imidazolyl)butyric acid (3.4 g, 75%). Colorless prisms. mp. 125°-126° C.

1. customwas subjected to catalytic hydrogenation at room temperature
2. filtrationThe catalyst was filtered off
3. concentrationthe filtrate was concentrated under reduced pressure
4. customthe crystals were recrystallized from ethanol