HuagongsheHuagongshe Chemistry Print Report · For research reference only
Thionyl Chloride → 4-(4-Fluorophenyl)butyryl chloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | 4-(p-Fluorophenyl)butyric acid | HCID 68524 | — |
| Product | 4-(4-Fluorophenyl)butyryl chloride | HCID 23293594 | 101.4% |
Reaction Steps
A mixture of 4-(4-fluorophenyl)butyric acid (68.2 g, 0.37 mol) and thionyl chloride (155 g, 1.3 mol) was refluxed for 1.25 h. The mixture was concentrated in vacuo to give 75.3 g (100%) of 4-(4-fluorophenyl)butyryl chloride)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05719186 |
| Source dataset | uspto-grants-1998_02 |
| ORD ID | ord-7ba1d7f5539b400a9213a6a23af62fd4 |
| Source note | uspto-grants-1998_02 |