Sodium Hydroxide → HCID 21849211, compound

Participants

Reaction Steps

2-Acetamido-1,3-diacetoxy-2-[4-(4-butylphenyl)butyl]propane (66.2 mg) was dissolved in 2 ml of methanol and 2 ml of a 1N aqueous sodium hydroxide solution was added thereto. The mixture was refluxed under heating for 4 hours. The solvent was distilled away and the residue was purified by silica gel thin layer chromatography (methanol:chloroform=1:4) to give 24.9 mg of 2-amino-2-[4-(4-butylphenyl)butyl]-1,3-propanediol as white crystals.

Provenance & Evidence