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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 862894Generated: October 30, 2026

Propoxyphenyl homohydroxysildenafil → Lodenafil

https://huagongshe.com/reaction/862894

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPropoxyphenyl homohydroxysildenafilHCID 135505037—
ReactantHCID 178440421HCID 178440421—
ProductLodenafilHCID 135452901—

Reaction Steps

1-methyl-5-[5-piperazinylsulphonyl)-2-n-propoxyphenyl]-3-n-propyl-1,6-dihydro-7H-pyrazolo[4,3-d]pyrimidin-7-one; and 5-{5-[4-(2-hydroxyethyl)piperazinylsulphonyl]-2-n-propoxyphenyl}-1-methyl-3-n-propyl-1,6-dihydro-7H-pyrazolo[4,3-d]-pyrimidin-7-one.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05719283
Source datasetuspto-grants-1998_02
ORD IDord-01493397e414472b97c5503be976c161
Source noteuspto-grants-1998_02