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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 862943Generated: October 25, 2026

Ethyl(RS)-1-(2-Methoxyphenyl)-3-(3,4-methylenedioxyphenyl)indene-2-carboxylate → Ethyl (RS)-1-(2-Methoxyphenyl)-3-(3,4-methylenedioxyphenyl)indane-2-carboxylate

https://huagongshe.com/reaction/862943

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthyl(RS)-1-(2-Methoxyphenyl)-3-(3,4-methylenedioxyphenyl)indene-2-carboxylateHCID 18969639—
CatalystPalladiumHCID 23938—
SolventEthanolHCID 702—
ProductEthyl (RS)-1-(2-Methoxyphenyl)-3-(3,4-methylenedioxyphenyl)indane-2-carboxylateHCID 18969635100%

Reaction Steps

To a solution of ethyl(RS)-1-(2-methoxyphenyl)-3-(3,4-methylenedioxyphenyl)indene-2-carboxylate (90 mg, 0.22 mmol) in EtOH (10 ml) was added 10% palladium on activated carbon (90 mg). The resulting suspension was shaken on a Parr hydrogenator at 60 psi H2 overnight, then was filtered through a pad of Celite. The filtrate was concentrated under reduced pressure to afford the title compound (90 mg, 100%), which was used without further purification.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05719182
Source datasetuspto-grants-1998_02
ORD IDord-469a768e5d5642b8bc0ffa58c3969f23
Source noteuspto-grants-1998_02