HuagongsheHuagongshe Chemistry Print Report · For research reference only
12-Methoxydodecanoate → 12-Methoxydodecanoyl chloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 12-Methoxydodecanoate | HCID 1420 | — |
| Reactant | Oxalyl chloride | HCID 65578 | — |
| Reactant | 12-Methoxy-N-(phenylmethyl)dodecanamide | HCID 9797119 | — |
| Solvent | Toluene | HCID 1140 | — |
| Product | 12-Methoxydodecanoyl chloride | HCID 19611759 | — |
Reaction Steps
Reaction Scheme 4 illustratively shows the preparation of 12-methoxy-N-(phenyl-methyl)dodecanamide wherein 12-methoxydodecanoic acid (8) is treated with oxalyl chloride in anhydrous toluene to form 12-methoxydodecanoyl chloride (9) which in turn reacts with benzylamine in methylene chloride to give the desired fatty acid amide (10).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05719290 |
| Source dataset | uspto-grants-1998_02 |
| ORD ID | ord-4e78bf597de7475db94dc9c252acf369 |
| Source note | uspto-grants-1998_02 |