Hexane → 4-(2-Phenylbenzoylamino)-benzoylchloride

HRID 863037Notes

Reaction equation

HRID 863037 reaction equation
[C:1]1([C:19]2[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=2)[C:2]([C:7]([NH:9][C:10]2[CH:18]=[CH:17][C:13]([C:14](O)=[O:15])=[CH:12][CH:11]=2)=[O:8])=[CH:3][CH:4]=[CH:5][CH:6]=1.CCCCCC.S(Cl)([Cl:33])=O>>[C:1]1([C:19]2[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=2)[C:2]([C:7]([NH:9][C:10]2[CH:18]=[CH:17][C:13]([C:14]([Cl:33])=[O:15])=[CH:12][CH:11]=2)=[O:8])=[CH:3][CH:4]=[CH:5][CH:6]=1

Participants

4

Reactant 3

HCID 8058HexaneHCID 24386Thionyl ChlorideHCID 105435024-[(2-phenylbenzoyl)amino]benzoic Acid

Product 1

HCID 114505014-(2-Phenylbenzoylamino)-benzoylchloride

Procedure

A mixture of 1.39 g of 4-[([1,1'-biphenyl]-2-carbonyl)amino]benzoic acid in 2.0 ml of thionyl chloride is heated on a steam bath for 1 hour. Cold hexane is added and the crystalline solid collected and dried to give 1.34 g of the desired product, m.p. 118°-120° C.

Workup

  1. temperatureis heated on a steam bath for 1 hour
  2. customthe crystalline solid collected
  3. customdried

Sources & evidence

ORD record
ord-301216aaebbd4eea9d44b3c93bc38501
Source dataset
uspto-grants-1998_02
Patent number
US05719278

Reaction notes

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