Sodium Hydroxide → HCID 23698996, compound

HRID 863040Notes

Reaction equation

HRID 863040 reaction equation
[C:1]1([CH2:7][C:8]2[CH:26]=[CH:25][CH:24]=[CH:23][C:9]=2[C:10]([NH:12][C:13]2[CH:22]=[CH:21][C:16]([C:17]([O:19]C)=[O:18])=[CH:15][CH:14]=2)=[O:11])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[OH-].[Na+:28]>C(O)C>[C:1]1([CH2:7][C:8]2[CH:26]=[CH:25][CH:24]=[CH:23][C:9]=2[C:10]([NH:12][C:13]2[CH:14]=[CH:15][C:16]([C:17]([O-:19])=[O:18])=[CH:21][CH:22]=2)=[O:11])[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=1.[Na+:28]

Participants

4

Reactant 2

HCID 14798Sodium HydroxideHCID 8765094Methyl 4-[[2-(Phenylmethyl)benzoyl]amino]benzoate

Product 1

HCID 23698996HCID 23698996, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

A mixture of 4.90 g of methyl 4-[[2-(phenyl-methyl)benzoyl]amino]benzoate in 100 ml of absolute ethanol and 3.50 ml of 10N sodium hydroxide is heated on a steam bath for 3 hours. The aqueous phase is filtered and the resulting solid collected and dried to give 4.25 g of the desired product m.p. 340°-346° C.

Workup

  1. temperatureis heated on a steam bath for 3 hours
  2. filtrationThe aqueous phase is filtered
  3. customthe resulting solid collected
  4. customdried

Sources & evidence

ORD record
ord-b577b9830ea74a7bb050e20954a5c268
Source dataset
uspto-grants-1998_02
Patent number
US05719278

Reaction notes

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