5-Fluoro-2-methylbenzoyl chloride → HCID 19699096, compound

HRID 863047Notes

Reaction equation

HRID 863047 reaction equation
[NH2:1][C:2]1[CH:23]=[CH:22][C:5]([C:6]([N:8]2[CH2:14][CH2:13][C:12]3[CH:15]=[N:16][NH:17][C:11]=3[C:10]3[N:18]=[CH:19][CH:20]=[CH:21][C:9]2=3)=[O:7])=[CH:4][CH:3]=1.[F:24][C:25]1[CH:26]=[CH:27][C:28]([CH3:34])=[C:29]([CH:33]=1)[C:30](Cl)=[O:31]>>[NH:17]1[C:11]2[C:10]3[N:18]=[CH:19][CH:20]=[CH:21][C:9]=3[N:8]([C:6]([C:5]3[CH:22]=[CH:23][C:2]([NH:1][C:30](=[O:31])[C:29]4[CH:33]=[C:25]([F:24])[CH:26]=[CH:27][C:28]=4[CH3:34])=[CH:3][CH:4]=3)=[O:7])[CH2:14][CH2:13][C:12]=2[CH:15]=[N:16]1

Participants

3

Reactant 2

HCID 27373835-Fluoro-2-methylbenzoyl chlorideHCID 19699088HCID 19699088, compound

Product 1

HCID 19699096HCID 19699096, compound

Procedure

As described for Example 2, 2 mmol of 6-(4-aminobenzoyl)-1,4,5,6-tetrahydropyrazolo[3,4-d]pyrido-[3,2-b]azepine is reacted with 2.2 mmol of 5-fluoro-2-methylbenzoyl chloride to give the product as a solid.

Sources & evidence

ORD record
ord-db0f37012e2f441d88037e9da18231ae
Source dataset
uspto-grants-1998_02
Patent number
US05719278

Reaction notes

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