HuagongsheHuagongshe Chemistry Print Report · For research reference only
Triethylamine → HCID 19699138, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | 6-(5-Fluoro-2-methylbenzoyl)aminopyridine-3-carbonyl chloride | HCID 15508250 | — |
| Reactant | 1,4,5,6-Tetrahydropyrazolo[3,4-d]thieno[3,2-b]azepine | HCID 135727046 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 19699138 | HCID 19699138 | — |
Reaction Steps
To a solution of 2 mmol of 1,4,5,6-tetrahydropyrazolo[3,4-d]thieno[3,2-b]azepine and 10 mmol of triethylamine in 25 ml of dichloromethane is added 4.2 mmol of 6-[(5-fluoro-2-methylbenzoyl)amino]pyridine-3-carbonyl chloride. After stirring overnight, the mixture is worked-up as described for Example 1, and the initial solid treated with 1N NaOH as described for Example 1 to give the product as a solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05719278 |
| Source dataset | uspto-grants-1998_02 |
| ORD ID | ord-0f1be0a2a74e443c94fa94ce3c26f404 |
| Source note | uspto-grants-1998_02 |