6-(5-Fluoro-2-methylbenzoyl)aminopyridine-3-carbonyl chloride → HCID 19699143, compound

HRID 863051Notes

Reaction equation

HRID 863051 reaction equation
[N:1]1[C:5]2=[C:6]3[CH:14]=[CH:13][CH:12]=[N:11][C:7]3=[N:8][CH2:9][CH2:10][C:4]2=[CH:3][N:2]=1.[F:15][C:16]1[CH:17]=[CH:18][C:19]([CH3:34])=[C:20]([CH:33]=1)[C:21]([NH:23][C:24]1[N:29]=[CH:28][C:27]([C:30](Cl)=[O:31])=[CH:26][CH:25]=1)=[O:22]>>[NH:1]1[C:5]2[C:6]3[CH:14]=[CH:13][CH:12]=[N:11][C:7]=3[N:8]([C:30]([C:27]3[CH:26]=[CH:25][C:24]([NH:23][C:21](=[O:22])[C:20]4[CH:33]=[C:16]([F:15])[CH:17]=[CH:18][C:19]=4[CH3:34])=[N:29][CH:28]=3)=[O:31])[CH2:9][CH2:10][C:4]=2[CH:3]=[N:2]1

Participants

3

Reactant 2

HCID 155082506-(5-Fluoro-2-methylbenzoyl)aminopyridine-3-carbonyl chlorideHCID 19699118HCID 19699118, compound

Product 1

HCID 19699143HCID 19699143, compound

Procedure

As described for Example 13, 4,5-dihydropyrazolo[3,4-d]pyrido[2,3-b]azepine is reacted with 6-[(5-fluoro-2-methylbenzoyl)amino]pyridine-3-carbonyl chloride to give the product as a solid.

Sources & evidence

ORD record
ord-9eb0b59b93324732803e63cfb70bae24
Source dataset
uspto-grants-1998_02
Patent number
US05719278

Reaction notes

Loading…