Dimethylformamide diethylacetal → N-Benzyloxycarbonyl-3(R,S)-ethoxycarbonyl-1,2,3,4-tetrahydroquinoline

Participants

Reaction Steps

The title compound is prepared analogously to Example 1s) starting from 1.5 g of N-benzyloxycarbonyl-1,2,3,4-tetrahydroquinoline-3(R,S)-carboxylic acid and 3.7 ml of N,N-dimethylformamide diethyl acetal and is purified by means of FC (100 g of silica gel, mobile phases D and B). This gives the title compound: Rf (A)=0.75; MS: (M)+ =339.

Provenance & Evidence