Bromine → HCID 19697814, compound

HRID 863231Notes

Reaction equation

HRID 863231 reaction equation
[CH2:1]([O:3][C:4]([CH:6]1[CH2:15][C:14]2[C:9](=[CH:10][CH:11]=[CH:12][CH:13]=2)[NH:8][CH2:7]1)=[O:5])[CH3:2].[Br:16]Br>>[Br:16][C:12]1[CH:13]=[C:14]2[C:9](=[CH:10][CH:11]=1)[NH:8][CH2:7][CH:6]([C:4]([O:3][CH2:1][CH3:2])=[O:5])[CH2:15]2

Participants

3

Reactant 2

HCID 24408BromineHCID 12415759Ethyl 1,2,3,4-tetrahydroquinoline-3-carboxylate

Product 1

HCID 19697814HCID 19697814, compound

Procedure

Analogously to Example 33b), starting from 410 mg of 3(R,S)-ethoxycarbonyl-1,2,3,4-tetrahydroquinoline and 0.11 ml of bromine, 6-bromo-3(R,S)-ethoxycarbonyl-1,2,3,4-tetrahydroquinoline is obtained: Rf (D)=0.15; MS: (M)+ =285.

Sources & evidence

ORD record
ord-19445327bd4446a99dc0231c3b8b7cea
Source dataset
uspto-grants-1998_02
Patent number
US05719141

Reaction notes

Loading…