HuagongsheHuagongshe Chemistry Print Report · For research reference only
Allyl bromide → HCID 19697684, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Allyl bromide | HCID 7841 | — |
| Reactant | Sodium bis(trimethylsilyl)amide | HCID 2724254 | — |
| Reactant | HCID 19697557 | HCID 19697557 | — |
| Reactant | HCID 22882392 | HCID 22882392 | — |
| Solvent | Toluene | HCID 1140 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | HCID 19697684 | HCID 19697684 | — |
Reaction Steps
The title compound is prepared starting from 3.0 g of N-benzyloxycarbonyl-2(R,S)-hydroxymethyl-3,4-dihydro-2H-1,4-benzoxazine, 2.75 g of sodium bis(trimethylsilyl)amide and 1.7 ml of 3-bromo-1-propene analogously to Example 61): Rf (D)=0.32; Rf (3:1 mixture of toluene and ethyl acetate)=0.61.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05719141 |
| Source dataset | uspto-grants-1998_02 |
| ORD ID | ord-2a02e691e296417a9ca23b3d95c27fe8 |
| Source note | uspto-grants-1998_02 |