HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzoic acid, 2-mercapto-, methyl ester → Methyl 2-[(2,2-dimethoxy-1-phenylethyl)thio]benzoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzoic acid, 2-mercapto-, methyl ester | HCID 21009 | — |
| Reactant | Sodium Methoxide | HCID 10942334 | — |
| Reactant | (1-Bromo-2,2-dimethoxyethyl)benzene | HCID 11064658 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | Methyl 2-[(2,2-dimethoxy-1-phenylethyl)thio]benzoate | HCID 19696486 | 70% |
Reaction Steps
In each case 10 ml of methyl 2-mercaptobenzoate and 2-bromo-1,1-dimethoxy-2-phenylethane are refluxed overnight in 30 ml of methanol, with addition of 10 ml of NaOMe. After working up and purification by chromatography, 70% of viscous oil is obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05721248 |
| Source dataset | uspto-grants-1998_02 |
| ORD ID | ord-45b10d4831e14fa7b388c364bec5fa8f |
| Source note | uspto-grants-1998_02 |