HCID 19696253, compound → HCID 19696236, compound

Participants

Reaction Steps

N-(5-Amino-6-bromo-4-nitro-indan-2-yl)-acetamide (0.7 g, 2.2 mmol) was dissolved in tetrahydrofuran (20 mL) and then treated with Raney nickel and stirred under a hydrogen atmosphere (1 atm) at room temperature for 1 h. The catalyst was removed by filtration through a celite pad, and washed repeatedly with methanol. The combined organic filtrate was removed by rotoevaporation to give a syrup that solidified upon standing. This product was used without further purification.

Provenance & Evidence