Nitric Acid → HCID 19696268, compound

Participants

Reaction Steps

A mixture of 9-pyrrolidin-1-yl-1,4,7,8,9,10-hexahydrobenzo[f]quinoxaline-2,3-dione hydrochloride (35 mg) in trifluoroacetic acid (2 mL) was cooled in an ice bath and treated with 0.5 mL fuming nitric acid. After 2 h at room temperature, the solvent was evaporated and the residue suspended in acetone:water, and the resulting solid collected by filtration (35 mg). Calc'd for C16H18N4O4.HCl: C, 52.39; H, 5.22; H, 15.27; found: C, 42.95; H, 4.69; N, 16.28. MS M+1 (331).

Provenance & Evidence