HCID 131720540, compound → HCID 67639109, compound

Participants

Reaction Conditions

Reaction Steps

A mixture of 1.0 g. of the ester obtained in step C and 0.1 powdered porous plate is heated, with stirring, in an oil bath at 210° C. under nitrogen, then dissolved in benzene and ether, filtered and extracted with sodium bicarbonate solution. The aqueous solution is filtered by suction to remove ether, neutralized with acetic acid, then acidified weakly with dilute hydrochloric acid. The crude product is then recrystallized from aqueous ethanol and dried in vacuo.

Provenance & Evidence