HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethanol → HCID 54318922, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethanol | HCID 702 | — |
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | Methyl [5-(4-methoxybenzoyl)-1-methyl-1H-pyrrol-2-yl]acetate | HCID 18424261 | — |
| Reactant | HCID 20566121 | HCID 20566121 | — |
| Solvent | Water | HCID 962 | — |
| Product | HCID 54318922 | HCID 54318922 | 87% |
Reaction Steps
A solution of 3.00 g. (0.0105 mole) of methyl 5-(ρ-anisoyl)-1-methylpyrrole-2-acetate in 12 ml. (0.012 mole) of 1N sodium hydroxide solution and 5 ml. of 95% ethanol is refluxed for 30 minutes. The solution is diluted with water and the ethanol is evaporated in vacuo. The solution is filtered, and the filtrate acidified with dilute hydrochloric acid. The precipitated solid is collected by filtration, dried and recrystallized from methanol-water to give about 2.4 g. (87% yield) of white-5-(ρ-anisoyl)-1-methylpyrrole-acetic acid, M.P. 170°-171° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05721347 |
| Source dataset | uspto-grants-1998_02 |
| ORD ID | ord-db14e6ff4a1c4bcf8f6672b2cbc07878 |
| Source note | uspto-grants-1998_02 |