Sodium Azide → HCID 19696341, compound

Participants

Reaction Steps

A solution of 500 mg of the pyrroledione product of Example 15 and 250 mg of sodium azide in 10 ml of dimethylformamide was heated at 70° C. for 3 hours. The solvent was removed by evaporation and the solid was partitioned between ethyl acetate and water. The insoluble material was filtered off and dried to give 425 mg of 3-[8-(2-azidoethyl)-6,7,8,9-tetrahydropyrido[1,2-a]indol-10-yl]-4-(1-methyl-3-indolyl)-1H-pyrrole-2,5-dione of melting point 262°-264° C.

Provenance & Evidence