Acetic acid, 2-chloro-, phenylmethyl ester → HCID 67745257, compound

Participants

Reaction Steps

7.6 g (0.1 mol) of thiourea were dissolved in 50 ml of acetone. 18.5 g (0.1 mol) of benzyl chloroacetate were added dropwise and the mixture was heated at the boil for two hours. After cooling down to room temperature, the precipitated product was filtered off and washed with diethyl ether. Drying left 23.5 g (corresponding to a yield of 90%) of the title compound in the form of colorless crystals. The product was more than 99% pure.

Provenance & Evidence