2-Bromobutanoic acid → 64037-76-9

HRID 863720Notes

Reaction equation

[NH2:1][C:2]([NH2:4])=[S:3].[Br:5][CH:6]([CH2:10][CH3:11])[C:7]([OH:9])=[O:8]>>[Br-:5].[C:7]([CH:6]([S:3][C:2]([NH2:4])=[NH2+:1])[CH2:10][CH3:11])([OH:9])=[O:8]

Participants

Reactant 2

HCID 66552-Bromobutanoic acid

HCID 2723790Thiourea

Product 1

HCID 8674987064037-76-9Yield 79%

Procedure

Example 1 was repeated with thiourea and 2-bromobutyric acid, affording the title compound in a yield of 79%.

Sources & evidence

ORD record: ord-5740b399b27c43c28b875ce39ad8c4ae
Source dataset: uspto-grants-1996_10
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05560814

Reaction notes

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