2-Chloro-2-methylpropanoic acid → 2-(2-Carboxy-2-propyl)thiouronium chloride

HRID 863721Notes

Reaction equation

[NH2:1][C:2]([NH2:4])=[S:3].[Cl:5][C:6]([CH3:11])([CH3:10])[C:7]([OH:9])=[O:8]>>[Cl-:5].[C:7]([C:6]([S:3][C:2]([NH2:4])=[NH2+:1])([CH3:11])[CH3:10])([OH:9])=[O:8]

Participants

Reactant 2

HCID 689872-Chloro-2-methylpropanoic acid

HCID 2723790Thiourea

Product 1

HCID 867498712-(2-Carboxy-2-propyl)thiouronium chlorideYield 74%

Procedure

Example 1 was repeated with thiourea and 2-chloro-2-methylpropionic acid, affording the title compound in a yield of 74%.

Sources & evidence

ORD record: ord-8d7633b50750475abde9e93da885c69e
Source dataset: uspto-grants-1996_10
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05560814

Reaction notes

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