HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium borohydride → Benzenemethanol, 2-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium borohydride | HCID 4311764 | — |
| Reactant | Benzaldehyde, 2-[[(1,1-dimethylethyl)dimethylsilyl]oxy]- | HCID 10900635 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | Benzenemethanol, 2-[[(1,1-dimethylethyl)dimethylsilyl]oxy]- | HCID 10966587 | 69.4% |
Reaction Steps
A solution of 28 (200 mg) in methanol (5.5 ml) containing NaBH4 (28 mg) is stirred for 1 hour at room temperature. 29 (140 mg, 68%) is obtained after hydrolysis and customary extraction.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05561119 |
| Source dataset | uspto-grants-1996_10 |
| ORD ID | ord-cface378f1e0442cb06387305829639a |
| Source note | uspto-grants-1996_10 |