6,7-Dimethoxy-1,2,3,4-tetrahydroisoquinoline hydrochloride → HCID 10579044, compound

Participants

Reaction Steps

The procedure of Example 3 is repeated using 4.3 g of α-(5-chlorohexyl)-3,4-dimethoxy-α-[(4-methylphenyl)thio]benzeneacetonitrile and 4.25 g of 6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline hydrochloride. This affords 3.05 g of the desired product as a golden gum. MS(CI): m/z 575. Calcd for C34H42N2O4S 1/8H2O: C=70.77, H=7.38, N=4.86, S=5.56 Found C=70.38, H=7.59, N=4.69, S=5.33

Provenance & Evidence