HuagongsheHuagongshe Chemistry Print Report · For research reference only
Phthalimide → a-(Cyclohexylthio)-alpha-(3,4-dimethoxyphenyl)-1,3-dioxo-2H-isoindole-2-heptanenitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Phthalimide | HCID 6809 | — |
| Reactant | Potassium | HCID 5462222 | — |
| Reactant | alpha-(5-Chloropentyl)-alpha-(cyclohexylthio)-3,4-dimethoxy-benzeneacetonitrile | HCID 11795020 | — |
| Product | a-(Cyclohexylthio)-alpha-(3,4-dimethoxyphenyl)-1,3-dioxo-2H-isoindole-2-heptanenitrile | HCID 10505769 | — |
Reaction Steps
The procedure of Example 24 is repeated using 2.1 g of α-(5-chloropentyl)-α-(cyclohexylthio)-3,4-dimethoxybenzeneacetonitrile and 0.954 g of the potassium salt of phthalimide. This affords 2.13 g of the desired product as a colorless oil. Calcd for C29H34N2SO4 : C=68.75, H=6.76, N=5.53, S=6.33 Found C=68.49, H=6.84, N=5.35, S=5.98
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05561141 |
| Source dataset | uspto-grants-1996_10 |
| ORD ID | ord-be8062b66edb4a358dd01ea9d2ac6d28 |
| Source note | uspto-grants-1996_10 |