Dimethyl Sulfoxide → 4-(1,3-Benzodioxol-5-yloxy)piperidine

HRID 864252Notes

Reaction equation

HRID 864252 reaction equation
COC1C=CC(N2C[C@H](C[N:15]3[CH2:20][CH2:19][CH:18]([O:21][C:22]4[CH:27]=[CH:26][CH:25]=[C:24]([O:28][CH3:29])[CH:23]=4)[CH2:17][CH2:16]3)OC2=O)=CC=1.CS(C)=[O:33]>>[CH2:29]1[O:33][C:25]2[CH:26]=[CH:27][C:22]([O:21][CH:18]3[CH2:17][CH2:16][NH:15][CH2:20][CH2:19]3)=[CH:23][C:24]=2[O:28]1

Participants

3

Reactant 2

HCID 679Dimethyl SulfoxideHCID 67694850HCID 67694850, compound

Product 1

HCID 49130284-(1,3-Benzodioxol-5-yloxy)piperidine

Procedure

3-p-methoxyphenyl-5(S)-[(4-m-methoxyphenoxypiperidino)methyl]-2-oxazolidinone (hydrochloride), m.p. 208°-209°; [α]D =-29.1° (DMSO);

Sources & evidence

ORD record
ord-f55a984210334a099f64e20f1e9a3afc
Source dataset
uspto-grants-1996_10
Patent number
US05561145

Reaction notes

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