HCID 356048, compound → HCID 53974719, compound

HRID 864308Notes

Reaction equation

HRID 864308 reaction equation
CN(C)C1C=CC=CC=1[CH:5]=[CH:6][C:7]1[N:12]=[C:11]([C:13]([O:15][CH2:16][CH3:17])=[O:14])[C:10]([C:18]([O:20][CH2:21][CH3:22])=[O:19])=[CH:9][C:8]=1[N+:23]([O-:25])=[O:24].C(O[C:34](OCC)([N:41](C)[CH3:42])C1C=CC=CC=1)C.CC1N=C(C(OCC)=O)C(C(OCC)=O)=CC=1[N+]([O-])=O>>[CH3:34][N:41]([CH3:42])[CH:5]=[CH:6][C:7]1[N:12]=[C:11]([C:13]([O:15][CH2:16][CH3:17])=[O:14])[C:10]([C:18]([O:20][CH2:21][CH3:22])=[O:19])=[CH:9][C:8]=1[N+:23]([O-:25])=[O:24]

Participants

4

Reactant 3

HCID 356048HCID 356048, compoundHCID 18937855HCID 18937855, compoundHCID 54470638HCID 54470638, compound

Product 1

HCID 53974719HCID 53974719, compound

Procedure

Diethyl 6-[2-(dimethylamino)styryl]-5-nitro-2,3-pyridinedicarboxylate is also prepared, using the above method, from N,N-dimethylbenzamide diethyl acetal and diethyl 6-methyl-5-nitro-2,3-pyridinedicarboxylate. A modification in the procedure of the latter is that upon cooling the dark red solution is partitioned between ether and water. The ethereal layer is separated and concentrated in vacuo to a dark red oil, which was carried on without purification.

Workup

  1. temperatureupon cooling the dark red solution
  2. customis partitioned between ether and water
  3. customThe ethereal layer is separated
  4. concentrationconcentrated in vacuo to a dark red oil, which
  5. customwas carried on without purification

Sources & evidence

ORD record
ord-a2a5cca464dc4fc69bc94f7ca12700e2
Source dataset
uspto-grants-1996_10
Patent number
US05563113

Reaction notes

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