HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetic Anhydride → Ethyl 2-(2,4,5-trifluoro-6-methylbenzoyl)-3-ethoxyacrylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetic Anhydride | HCID 7918 | — |
| Reactant | Ethyl orthoformate | HCID 31214 | — |
| Reactant | Ethyl (3,4,6-Trifluoro-2-methylbenzoyl)acetate | HCID 14517129 | — |
| Product | Ethyl 2-(2,4,5-trifluoro-6-methylbenzoyl)-3-ethoxyacrylate | HCID 54242925 | 90% |
Reaction Steps
To ethyl 2-methyl-3,4,6-trifluorobenzoylacetate (3.2 g) are added acetic anhydride (3.0 g) and triethoxymethane (2.7 g) and the mixture is refluxed for 1 hour. After concentrating, ethyl 2-(2-methyl-3,4,6-trifluorobenzoyl)-3-ethoxyacrylate (3.5 g) is obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05563138 |
| Source dataset | uspto-grants-1996_10 |
| ORD ID | ord-06c24156db784e84baaaefb210fae339 |
| Source note | uspto-grants-1996_10 |