HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Hydroxide → 5-bromo-6-methoxy-1H-indole-2-carboxylic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Hydroxide | HCID 14797 | — |
| Reactant | methyl 5-bromo-6-methoxy-1H-indole-2-carboxylate | HCID 16726758 | — |
| Product | 5-bromo-6-methoxy-1H-indole-2-carboxylic acid | HCID 19418869 | — |
Reaction Steps
Following the general procedure of PREPARATION 63 and making non-critical variations but starting with methyl 5-bromo-6-methoxyindole carboxylate (PREPARATION 81, 3.31 g) and potassium hydroxide (0.98 g), the title compound is obtained, NMR (300 MHz, CD3OD) 7.79, 7.03, 7.01 and 3.89 δ.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05563142 |
| Source dataset | uspto-grants-1996_10 |
| ORD ID | ord-62808255a3494311863925c11acc816f |
| Source note | uspto-grants-1996_10 |