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HRID864418

反应详情

EQUATION

反应方程式

HRID 864418 的结构方程式

REACTANTS

反应物

2
结构：[K+].[OH-]
HCID14797

Potassium hydroxide

HKO

结构：COC(=O)c1cc2c(C)cccc2[nH]1
HCID4714967

methyl 4-methyl-1H-indole-2-carboxylate

C11H11NO2

PRODUCTS

生成物

1
结构：Cc1cccc2[nH]c(C(=O)O)cc12
HCID3926087

4-Methyl-1H-indole-2-carboxylic acid

C10H9NO2

PROCEDURE

实验过程

Following the general procedure of PREPARATION 63 and making non-critical variations but starting with methyl 4-methylindole-2-carboxylate (PREPARATION 85, 4.94 g), potassium hydroxide (1.75 g), the title compound is obtained, NMR (300 MHz, CD3OD) 7.24, 7.19, 7.12, 6.85 and 2.51 δ.

WORKUP

后处理

  1. customthe general procedure of PREPARATION 63