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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 864836Generated: October 26, 2026

Benzenepropanoic acid, 4-hydroxy-, methyl ester → Methyl 3-[4-[1-(4-pyridyl)piperidin-4-yl]methoxyphenyl]propionate

https://huagongshe.com/reaction/864836

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzenepropanoic acid, 4-hydroxy-, methyl esterHCID 79706—
Reactant(1-(Pyridin-4-YL)piperidin-4-YL)methanolHCID 11310048—
ProductMethyl 3-[4-[1-(4-pyridyl)piperidin-4-yl]methoxyphenyl]propionateHCID 1891856814%

Reaction Steps

Following the method of Example 155, but starting from 4-(4-hydroxymethylpiperidin-1-yl)pyridine and methyl 3-(4-hydroxyphenyl)propionate, the title compound was prepared in 14% yield:

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05563141
Source datasetuspto-grants-1996_10
ORD IDord-3af6014d57c742cfb5788614fe0af40d
Source noteuspto-grants-1996_10