2-chloro-6H-thieno[2,3-b]pyrrole-5-carbonyl chloride → 2-{6-[(2-Chloro-6H-thieno[2,3-b]pyrrole-5-carbonyl)-amino]-5-ethoxy-pyridin-3-yl}-2-hydroxy-propionic acid ethyl ester

HRID 86485Notes

Reaction equation

HRID 86485 reaction equation
[CH2:13]([CH3:14])[O:15][C:16]([C:17]([CH3:18])([OH:19])[c:20]1[cH:21][n:22][c:23]([NH2:29])[c:24]([O:26][CH2:27][CH3:28])[cH:25]1)=[O:30].[Cl:1][c:2]1[cH:3][c:4]2[c:5]([nH:6][c:7]([C:9](=[O:10])[Cl:11])[cH:8]2)[s:12]1>>[Cl:1][c:2]1[cH:3][c:4]2[c:5]([nH:6][c:7]([C:9](=[O:10])[NH:29][c:23]3[n:22][cH:21][c:20]([C:17]([C:16]([O:15][CH2:13][CH3:14])=[O:30])([CH3:18])[OH:19])[cH:25][c:24]3[O:26][CH2:27][CH3:28])[cH:8]2)[s:12]1

Participants

3

Reactant 2

HCID 222527012-chloro-6H-thieno[2,3-b]pyrrole-5-carbonyl chlorideHCID 235938112-(6-Amino-5-ethoxy-pyridin-3-yl)-2-hydroxy-propionic acid ethyl ester

Product 1

HCID 695463622-{6-[(2-Chloro-6H-thieno[2,3-b]pyrrole-5-carbonyl)-amino]-5-ethoxy-pyridin-3-yl}-2-hydroxy-propionic acid ethyl ester

Sources & evidence

ORD record
ord-fe6d971ef88142bcb650bb63df3c4678
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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