Acetone → HCID 19419334, compound

Participants

Reaction Steps

A mixture consisted of 3.15 g (18.2 mmol) of 2-ethyl-6-hydroxy-1-nitrobenzene, 4.44 g (36.7 mmol) of allyl bromide, 2.70 g (19.5 mmol) of potassium carbonate, 262 mg (1.75 mmol) of sodium iodide and 30 ml of acetone was heated under refluxing for 2 hours. After cooling, the reaction mixture was diluted with ether and the diluted mixture was filtered to remove inorganic substances. The filtrate was concentrated and the concentrate was purified by column chromatography through 150 g of silica gel using a 1:9 mixture of ether and hexane as an eluent to give 3.68 g (98%) of the title compound as an oil.

Provenance & Evidence