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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 864983Generated: November 1, 2026

Trehalose → (2R,3S,4R,5R)-2,3,4,5,6-pentahydroxyhexanal

https://huagongshe.com/reaction/864983

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTrehaloseHCID 7427—
SolventSulfuric AcidHCID 1118—
Product(2R,3S,4R,5R)-2,3,4,5,6-pentahydroxyhexanalHCID 107526—

Reaction Conditions

Temperature100 °C

Reaction Steps

The 250 MHz proton NMR spectral patterns of the white powder thus obtained are identical with those of commercially available trehalose. The white powder is found negative in the Somogyi-Nelson reducing sugar test. Furthermore, the white powder is dissolved in 0.05 N sulfuric acid to make a 20 mM solution, heated at 100° C. for 15 hours in a closed container to give 37 mM glucose according to an HPLC measurement.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05565341
Source datasetuspto-grants-1996_10
ORD IDord-38aa3c230bc84a058d8dcfeb682d692b
Source noteuspto-grants-1996_10